Wopanga Tamoxifen Citrate powder (54965-24-1) Wopanga - Buyaas

Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1)

November 8, 2018
SKU: 54965-24-1
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
(1 kasitomala review)

Tamoxifen Citrate powder ndi mankhwala osagwiritsa ntchito mankhwala omwe ali ndi antiestrogen. Anti-estrogens amagwira ntchito poletsa zotsatira za hormone estrogen mu thupi. Estrogen ingapangitse kukula kwa mitundu ina ya zotupa za m'mawere. Tamoxifen ingalepheretse kukula kwa zotupa zomwe zimayankha estrogen.


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

Mavidiyo akuluakulu a Tamoxifen Citrate powder (54965-24-1)

Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1) Ndemanga

Mafuta akuluakulu a Tamoxifen Citrate powder ndi salt citrate ya antiinoplastic ossteroidal kusankha estrogen receptor modulator (SERM). Tamoxifen mpikisano amalepheretsa kumangiriza kwa estradiol kwa maselo a estrogen, motero kuteteza kuti cholowacho chisamangidwe ku gawo la estrogen-response pa DNA. Zotsatira zake ndi kuchepa kwa DNA kaphatikizidwe ndi ma selojeni kwa estrogen. Kuonjezera apo, tamoxifen imayambitsa kupanga kusinthika kwa factor B (TGFb), chomwe chimapangitsa kuti tizilombo toyambitsa matenda tizilombo, komanso kuchepetsa mphamvu ya insulini yofanana ndi 1 (IGF-1), chomwe chimayambitsa khansa ya m'mawere . Tamoxifen imakhalanso pansi-kuteteza mafotokozedwe a puloteni kinase C (PKC) m'njira yotengera mlingo, kulepheretsa kutengako ma signal ndi kutulutsa zotsatira zotsutsana ndi ziphuphu monga glioma yoopsa ndi khansa zina zomwe zimawononga PKC.

Mafuta akuluakulu a Tamoxifen Citrate ufa umagwiritsidwa ntchito pochiza ndi kupewa tizilombo toyambitsa matenda a estrogen. Tamoxifen amachititsa kukhala anti-estrogen (kuletsa wothandizira) minofu ya mammary, koma monga estrogen (wothandizira) mu cholesterol kagayidwe kake, minofu ya mafupa, ndi kuchulukana kwa maselo mu endometrium.

Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1) Szizindikiro

Name mankhwala Mpweya waukulu wa Tamoxifen Citrate powder
Mankhwala Name Chosokoneza; Tamoxifen,
Brand NAme Nolvadex
Kalasi ya Mankhwala chisamaliro cha estrogen receptor modulator (SERM)
Nambala ya CAS 54965-24-1
InChIKey FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Maselo Fmphutsi C32H37NO8
Maselo Wasanu ndi atatu 563.647 g / mol
Misa ya Monoisotopic 563.252 g / mol
Kusungunula Pmafuta 97 ° C
Fkubwezeretsanso Pmafuta Palibe deta yomwe ilipo
Halimo Half-Life Kuchepa kwa tamoxifen m'magazi a pulasitiki ndi biphasic yomwe imatha kufafaniza theka la moyo wa pafupifupi 5 kwa masiku 7. Nthenda ya moyo ya N-desmethyl tamoxifen ndi masiku 14.
mtundu White kapena off-woyera woyera
Kutupa madzi okwanira 0.000167 mg / mL pa 25 ° C
yosungirako Tkutentha 2-8 ° C
Amalingaliro gwiritsani ntchito kuchiza ndi kupewa kansera ya m'mawere yotchedwa estrogen receptor.

Kodi Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1)?

Tamoxifen ndi mtundu wa mankhwala otchedwa hormone mankhwala otchedwa estrogen receptor modulator (SERM). Chimodzi mwa mayina a dzina la tamoxifen ndi Nolvadex.

Kodi Tamoxifen Citrate ufa wochuluka bwanji (54965-24-1) ntchito

Tamoxifen amagwira ntchito poyandikira maselo a estrogen m'maselo a m'mawere kuti estrogen isathe kuwamangiriza. Popewera estrogen m'matumbo omwe amamanga mapuloteni, tamoxifen amachepetsa kukula ndi kubereka kwa maselo a khansa ya m'mawere.

Tamoxifen Citrate powder ndi salt citrate ya antiinoplastic nonsteroidal kusankha estrogen receptor modulator (SERM). Tamoxifen mpikisano amalepheretsa kumangiriza kwa estradiol kwa maselo a estrogen, motero kuteteza kuti cholowacho chisamangidwe ku gawo la estrogen-response pa DNA. Zotsatira zake ndi kuchepa kwa DNA kaphatikizidwe ndi ma selojeni kwa estrogen. Kuonjezera apo, tamoxifen imayambitsa kupanga kusinthika kwa factor B (TGFb), chomwe chimapangitsa kuti tizilombo toyambitsa matenda tizilombo, komanso kuchepetsa mphamvu ya insulini yofanana ndi 1 (IGF-1), chomwe chimayambitsa khansa ya m'mawere . Tamoxifen imakhalanso pansi-kuteteza mafotokozedwe a puloteni kinase C (PKC) m'njira yotengera mlingo, kulepheretsa kutengako ma signal ndi kutulutsa zotsatira zotsutsana ndi ziphuphu monga glioma yoopsa ndi khansa zina zomwe zimawononga PKC.

Mphungu yaikulu ya Tamoxifen Citrate powder (54965-24-1) Mlingo

Werengani Buku la Mankhwala loperekedwa ndi wamankhwala anu musanayambe kugwiritsa ntchito tamoxifen ndipo nthawi iliyonse mukakonzanso. Ngati muli ndi mafunso alionse, funsani dokotala kapena wamankhwala.

Tengani mankhwalawa pakamwa kapena popanda chakudya, kawirikawiri kamodzi kapena kawiri pa tsiku kwa zaka 5, kapena monga mwadokotala wanu. Mankhwala tsiku lililonse kuposa mamiliyoni a 20 amagwiritsidwa ntchito theka ndi kutengedwa kawiri patsiku, m'mawa ndi madzulo, kapena monga mwadokotala wanu. Ngati mukugwiritsa ntchito madziwa, yesani mlingo moyenera pogwiritsa ntchito chipangizo chapadera choyezera / supuni. Musagwiritse ntchito supuni ya banja chifukwa simungapeze mlingo woyenera.

Mlingo umachokera pa matenda anu ndi kuyankha kwa mankhwala.

Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1) ubwino

Tamoxifen ndilo kusankha koyamba kwa amayi omwe ali ndi chikhalidwe choyambirira ndipo akadakali chisankho chabwino kwa amayi omwe amatha kupha amayi omwe sangathe kutenga aromatase inhibitor.

Tamoxifen akhoza:

  • Kuchepetsa chiopsezo cha khansa ya m'mawere kubwereranso ndi 40% mpaka 50% mwa amayi omwe amachititsa mkhalidwe wamagazi ndi 30% mpaka 50% mwa amayi omwe ali ndi vutoli
  • Kuchepetsa chiopsezo cha khansara yatsopano yomwe ikukula mchifuwa china pafupi ndi 50%
  • Pewani makanswe akuluakulu, omwe amachititsa kuti musamayambe opaleshoni
  • Pang'onopang'ono kapena kuima khansara yapamwamba (metastatic) ya hormone-receptor-positive m'mawa onse awiriwa
  • Gwiritsani ntchito chiopsezo cha khansa ya m'mawere kwa amayi omwe ali ndi chiopsezo chachikulu kuposa matenda omwe sanapeze

Tamoxifen imapereka zithandizo zina zamankhwala zosagwirizana ndi kuchiza khansa. Chifukwa ndi SERM, imasankha kapena imasintha zochita za estrogen pa maselo enaake. Ngakhale tamoxifen imaletsa zochita za estrogen pa maselo a m'mawere, zimayambitsa maselo a estrogen m'maselo ndi mafupa a chiwindi. Choncho tamoxifen akhoza:

  • Thandizani kusiya kuchepa kwa mafupa pambuyo pa kutha kwa nthawi
  • makilogalamu otsika kwambiri

Gulani Tamoxifen Citrate powder kuchokera ku Buyaas.com

Tithandizana nafe, tingathe kuchita izi:
1. Zogulitsa zathu zimapangidwa pansi pa cGMP ndipo khalidwe likhoza kuwonekera.
2. Chiyero chiri Chotsimikiziridwa zosachepera 98%. COA; HPLC; Malipoti a mayeso a HNMR angaperekedwe.
3. Mphamvu zathu zopezera zogwirira ntchito zimakhala zolimba kwambiri komanso zimapangidwira kupanga nthawi zambiri.
4. Tili ndi mwayi wochuluka potumikira misika yam'mwamba pamtunda padziko lonse lapansi.
5. Gwirizanitsani ndi fakitale yathu mwachindunji, mukhoza kuchepetsa mtengo wanu.


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Mafotokozedwe ndi zolemba zamagulu

Njira Yabwino Kwambiri Yothandiza Nolvadex kuti yodwala khansa ya m'mawere

Zothandizira

  1. Tamoxifen: Pambuyo pa Antiestrogen, Ndi John A. Kellen, tsamba 1-201
  2. John F. Kessler, Greg A. Annussek, HarperCollins, 6 April 1999, 1-208
  3. Tamoxifen, Dr. Titus Marcus, Wofalitsidwa Mwaulere, 29thMarch 2019, 1-18
1 review kwa Mafuta akuluakulu a Tamoxifen Citrate powder (54965-24-1)
  1. 5 kuchokera 5

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    Chomera cha TAMOXIFEN CITRATE POWDER chimathandiza kwambiri.

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